IMID Medical Journal

   Complex immune neuroendocrine interactions rediscover the traditional power and efficiency of italian school of internal medicine: the interdisciplinary IMID method guarantees accuracy in medical treatments, savings in management and a reduction of cognitive errors. One of the major criteria for subdividing internal medicine into easy-to-manage subcategories, has been the conventional privilege for those anatomic areas in which the disease was manifesting itself. Clearly, the classification of diseases according to this standard was closely connected to symptoms. Later on, this criteria will be rated as strongly influenced by the incomplete knowledge of the pathogenesis of diseases and by the mistaken or absent knowledge of etiology. Current models have been criticised by many, because of their tendency to underestimate the chronicity of the most widespread or expanding diseases, as well as the underlying cause or causes. This paper focuses on C.R.P.S. (Complex Regional Pain Syndrome), whose symptoms are pain, dysfunctional, circulatory and trophic phenomena. These syndromes, even multiple-etiology disease syndromes, have always been characterised by pathogenetics mechanisms implicating neuroendocrine functions and by modifications in the involved cell populations. The knowledge and the criteria IMID’s thinking feeds on and works with, have been of extreme heuristic value so far, and makes possible the application of high-efficiency, versatile, and economical therapeutic protocols.