Chemoantibiotics

Adverse reactions to chemoantibiotics

   The most recent and reliable world statistics show that chemoantibiotics are responsible for approximately 40-50% of cases of adverse drug reaction. Chemoantibiotics adverse reactions (CAR), considering such prevalence, are therefore becoming more relevant every day in clinical medicine, both for reasons that are inherent in their morbidity and mortality rates, and for consequences arising from the necessity of suspending the administration of a drug that possibly caused an adverse reaction, especially when such drug is the first choice of treatment of a particular condition. All the classes of chemoantibiotics can potentially cause adverse reactions. In terms of frequency, β-lactams are the most common cause among antimicrobial agents; they are followed by sulfonamides, fluoroquinolones, glycosylamines, macrolides and tetracyclines.

 

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